About the CCTS

Accelerating Discoveries, Improving Health

Kentucky and Appalachia experience some of the nation's most severe health disparities: Eight of thirteen counties recently found to have a declining life expectancy are in the Commonwealth, and the region is currently the epicenter of the opioid epidemic, with overdose deaths in Kentucky hitting record highs in 2017. Through research funding, training, infrastructure, and community engagement, we facilitate innovative team science to address these and other critical health issues. 

JAMA Map 2017

Since 2006, the CCTS has catalyzed clinical and translational discoveries through an integrated, transformative research environment aimed at improved health, with emphasis on Central Appalachia.

Timeline of CCTS evolution from 2006-2011



Our Impact


ROI for Pilot Funding Program 


National Partnerships through 2019


Pilot Awardees with at Least One Publication 

In the News

  • Parents are 'Proud Our Daughters are Doing Their Part' in Vaccine Research Trial
    • Oct 12 2021

    Tegan, Piper and Josie Stanifer, daughters of UK College of Nursing researcher Stacy Stanifer, volunteered to be a part of the clinical trial that tests the efficacy of Modern COVID vaccine in children under 11 years old.

  • Opinion: Herd immunity is almost here. But what does that mean?
    • Oct 8 2021

    Opinion by John M. Barry 10/7/2021 at 4:59 p.m. EDT John M. Barry is the author of “The Great Influenza: The Story of the Deadliest Pandemic in History” and distinguished scholar at Tulane University’s School of Public Health and Tropical Medicine.

  • UK Receives $23.5 Million Clinical and Translational Science Award from the NIH
    • Sep 14 2021

    The University of Kentucky Center for Clinical and Translational Science (CCTS) has received a $23.5 million, four-year award from the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health. This is the third time the CCTS has successfully competed for the prestigious Clinical and Translational Award (CTSA), with continuous funding since 2011 totaling $65.4 million in research dollars.

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