Objectives:
- Appreciate the importance of identifying key mechanisms and new potential drug targets in ischemic stroke.
- Understand the importance of extracellular vesicles, perfusion imaging, and information that can be gleaned from important biomarkers within.
- Develop an understanding of the need for new therapies and advanced imaging in ischemic stroke patients.
The BACTRAC tissue bank was developed as a collaborative opportunity for basic, translational, and clinical researchers and surgeon-scientists. This endeavor fostered dozens of publications and has led to new grants and research avenues, including EV isolation/analysis, proteomics, and platelet biology. PRISM builds upon the BACTRAC foundation, leveraging real-time perfusion imaging during ischemic stroke paired with intracranial blood sampling to develop a better understanding of the ischemic stroke microenvironment and to identify new therapeutic targets to offset secondary injury in stroke patients.
Presented by:
- Justin Fraser, MD, FAANS, FAHA, FCNS
Professor and Vice-Chair
Neurological Surgery
University of Kentucky - Amanda Trout, PhD
Assistant Professor
Department of Neurology
University of Pittsburgh - David Dornbos III, MD, FAANS, FCNS
Assistant Professor
Neurological Surgery
University of Kentucky
