NCATS is accepting pre-proposals to collaborate with the Center’s intramural scientists to advance promising compounds, drug candidates, and human cell-based models for pain, addiction, and overdose through pre-clinical development. The research collaborations are part of the NIH HEAL (Helping to End Addiction Long-term℠) Initiative. Pre-proposals will be accepted on a rolling basis. The first pre-proposal deadline is March 18, with full proposals due on April 22.