Researchers at the University of Kentucky are conducting a study to learn how two different medications that are used to treat opioid use disorder affect the health of patients who are HIV-positive. We will be learning about a drug called Extended-Release Naltrexone.
We hope to find out if using the study drug can control HIV better than treatment as usual for opioid use disorder in patients who are HIV-positive.
You may be eligible to participate if you:
- Are 18 or older
- Have moderate or severe opioid use disorder
- Have an unsuppressed HIV viral load
- Are willing to provide written informed consent
- Are willing to be randomized to study drug or treatment as usual
- Are willing to establish ongoing HIV care if not already receiving care
If you are eligible and decide to participate:
- You will complete the informed consent process and screening interview
- You will have a 50/50 chance of being in either two study groups: study drug or treatment as usual
- You will be asked to attend study visits once a month, as well as visits to your HIV care provider as needed
- Your participation will be about 6-7 months
You will be compensated for your participation.
This study is being funded by the National Institute on Drug Abuse.
Principal Investigator: Laura Fanucchi, MD