Comparing treatments for HIV-infected opioid users in an integrated care effectiveness study (CHOICES)
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Researchers at the University of Kentucky are conducting a study to learn how two different medications that are used to treat opioid use disorder affect the health of patients who are HIV-positive. We will be learning about a drug called Extended-Release Naltrexone.

We hope to find out if using the study drug can control HIV better than treatment as usual for opioid use disorder in patients who are HIV-positive.

You may be eligible to participate if you:

  • Are 18 or older
  • Have moderate or severe opioid use disorder
  • Have an unsuppressed HIV viral load
  • Are willing to provide written informed consent
  • Are willing to be randomized to study drug or treatment as usual
  • Are willing to establish ongoing HIV care if not already receiving care

If you are eligible and decide to participate:

  • You will complete the informed consent process and screening interview
  • You will have a 50/50 chance of being in either two study groups: study drug or treatment as usual
  • You will be asked to attend study visits once a month, as well as visits to your HIV care provider as needed
  • Your participation will be about 6-7 months

You will be compensated for your participation.

This study is being funded by the National Institute on Drug Abuse.
Principal Investigator: Laura Fanucchi, MD


If you are interested in learning more about this study, please complete this form:
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How did you hear about this study?
ResearchMatch.org, KY Women's Health, Sanders-Brown, etc.
CISCRP, Clinicaltrials.gov, CenterWatch, etc.